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management rheumatology syndrome antinxp2 antinxp2dm calcifications clincial dermatology dermatomyositis encephalopathy igg4 infant lichen neurology phenotypes photo posterior pres radiology related
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... deficiency, or Wolman’s disease ... and gut, which causes ... #clincial #peds ... #infant #NEJM #
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... Although the cause ... an autoimmune disease ... #NEJM #clinical ... #derm #wickhams
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... pancreas, biliary, renal ... aorta, salivary glands ... supporting long-term
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Syphilis - Clinical ... responsible for most cases ... loss • Skin: Rash ... meningovascular disease ... Syphilis #stages #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... epilepticus Treatment ... the underlying cause ... • Treatment of ... until cause identified
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary and lacrimal glands ... Sjogren's Syndrome Diagnosis ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Violaceous papules or plaques ... auricular papules Clinical ... Muscle atrophy may cause ... had more severe disease ... positive patients Treatment
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