10 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... deficiency, or Wolman’s disease ... and gut, which causes ... #clincial #peds ... #infant #NEJM #
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... an autoimmune disease ... used in primary treatment ... #NEJM #clinical ... #derm #wickhams
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... pancreas, biliary, renal ... aorta, salivary glands ... supporting long-term
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... responsible for most cases ... loss • Skin: Rash ... meningovascular disease ... Syphilis #stages #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... mucositis - Rash ... testes -> pain, infarct
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
Newborn Infant - ... When the diagnosis ... 160 beats/min in term ... #Examination #Peds ... #Pediatrics #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Shock, Autoimmune disease ... epilepticus Treatment ... the underlying cause ... • Treatment of ... until cause identified
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary and lacrimal glands ... Sjogren's Syndrome Diagnosis ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... ulcer or indurated plaque ... failure, infant ... University Infectious Diseases ... dermatology #skin #clinical
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Violaceous papules or plaques ... auricular papules Clinical ... Muscle atrophy may cause ... had more severe disease ... positive patients Treatment