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diagnosis differential management rheumatology vasculitis autoimmune classification dermatology exanthematous generalized gravis hematology hiv leukemia myasthenia myopathy myositis neurology oncology pustulosis
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
1) 4) Average age ... renal failure Clinical ... symptoms are not caused ... nodes: 13-15%, skin ... : ACUTE, fever,
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Syndrome Acute ... sweats (28%) • Skin ... rash (48%) • ... 14%), in which case ... Epstein-Barr virus (EBV
Acute Generalized Exanthematous Pustulosis (AGEP) AGEP is largely a clinical diagnosis based on classical skin findings in
Acute Generalized ... a clinical diagnosis ... Causes? ... Clinical Presentation ... During the acute
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Cytopenia -> BM ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... glomerulonephritis) • Anti-GBM ... mucositis - Rash ... Takayasu: - Age ... temporal artery - Age
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Epidemiology: - Bimodal age ... Clinical Picture ... Clinical DX: - ... aspiration and acute ... immunosuppressants - Meds
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Takayasu: • Age ... temporal artery • Age ... , mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Syphilis - Clinical ... weight loss • Skin ... : Rash is the most ... Albuminuria, nephrotic syndrome ... , or acute nephritis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... MYOSITIS: • M > F • Age ... • ANA < 20 % IBM ... statins - probably caused
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