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diagnosis rheumatology management differential vasculitis autoimmune classification dermatology erythematosus exanthematous generalized gravis hematology hiv leukemia lupus myasthenia myopathy neurology oncology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
1) 4) Average age ... renal failure Clinical ... symptoms are not caused ... nodes: 13-15%, skin ... : ACUTE, fever,
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Syndrome Acute ... sweats (28%) • Skin ... rash (48%) • ... 14%), in which case ... Epstein-Barr virus (EBV
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Conjunctivitis, mucositis ... - Rash, arthritis ... Takayasu: - Age ... temporal artery - Age
Acute Generalized Exanthematous Pustulosis (AGEP) AGEP is largely a clinical diagnosis based on classical skin findings in
Acute Generalized ... a clinical diagnosis ... Causes? ... Clinical Presentation ... During the acute
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Cytopenia -> BM ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Classification: • Acute ... Clinical Features ... Pleural effusions • Acute
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Takayasu: • Age ... temporal artery • Age ... • Rash, arthritis ... tract, and often causes ... pain and GN Anti-GBM
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Epidemiology: - Bimodal age ... Clinical Picture ... Clinical DX: - ... aspiration and acute ... immunosuppressants - Meds
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Syphilis - Clinical ... weight loss • Skin ... : Rash is the most ... Albuminuria, nephrotic syndrome ... , or acute nephritis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Decades (can be any age ... Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... neuropathy, transverse myelitis
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