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rheumatology lupus druginduced hemophagocytic hlh lymphohistiocytosis summary syndrome treatment comparison crisis dermatology erythematosus hemeonc macrophage mas monkeypox nephrology photo renal
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... 40, F:M 9:1 • Clinical ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... versus DIL • ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Petechial or purpuric rash ... erythematosus [SLE ... #Syndrome #Diagnosis ... #Management #Hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... diagnosis #treatment ... #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Hematologic: ... #Diagnosis #Management
Monkeypox Skin Rash 30 yr F and her 6 yr daughter purchased 2 prairie dogs 10 days
dogs 10 days ago (pers ... Diagnosis? ... #Monkeypox #SkinRash ... #clinical #photo ... #dermatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis (SRC) Clinical ... endothelial cell activation ... , add other BP meds ... • Refractory cases ... #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... hyperinflammatory syndrome caused ... Clinical Presentation ... #Management #Hematology
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