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differential dermatology vasculitis antimda5dm antinxp2 antinxp2dm autoimmune classification management myopathy myositis vasculitides
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... onset [33-74%] • Blood ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Muscle atrophy may cause ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... purpura: strong sign ... Large Vessel: Blood ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... pulses, bruits, or blood ... , mucositis • Rash ... tract, and often causes ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... muscle weakness PE ... statins - probably caused
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