11 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... and gut, which causes ... #clincial #peds ... #adrenal #calcifications ... #infant #NEJM #
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
depressed) • Renal ... anaphylaxis, toxins/meds ... vomiting/diarrhea), renal ... O2 delivery • PE ... #differential #causes
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
depressed) • Renal ... anaphylaxis, toxins/meds ... vomiting/diarrhea), renal ... O2 delivery • PE ... #differential #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... tract, and often causes ... mucositis - Rash ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, DIC, hypoTN, renal ... maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
, DIC, hypoTN, renal ... maculopapular rash ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... , mucositis • Rash ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... effusion, INC risk PE ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... Sjogrens #Syndrome #Rheumatology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Scleroderma Renal ... of Scleroderma Renal ... , add other BP meds ... • Refractory cases ... #Crisis #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... Muscle atrophy may cause ... • Clear cell renal ... diagnosis #management #rheumatology