11 results
Subacute Cutaneous Lupus erythematosus (SCLE): Erythematous, warm, plaques in light exposed distribution (also on patient's neck),
Lupus erythematosus ... (SCLE): Erythematous ... Lupus Erythematosus ... #Lupus #Erythematosus ... #SCLE #Photo #UCSDH
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... lupus erythematosus ... rashErythematous ... #Systemic #Lupus
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have ... like “butterfly rash
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
M DAMN SHARP - Lupus ... Neurological Disorders ... #IMDAMNSHARP #sle ... #systemic #lupus ... #erythematosus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Rare (SSA+ for cutaneous ... months to years) Systemic ... Lupus Erythematosus ... #sle #comparison
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... , Cutaneous mimickers ... #Systemic #Lupus ... #Erythematosus
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin Rash ... Differential Diagnosis Algorithm ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin Rash ... Erythrematous ... soles • Discoid Lupus ... Erythematous - ... Papulosquamous #SkinRash
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic ... lupus erythematosus ... (SLE), rheumatoid
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... aphthous ulcers, cutaneous ... lupus erythematosus ... strong sign of cutaneous ... vasculitis, and SLE