6 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
• Periorbital heliotrope ... Clinical and ... 74% of anti-MDA5 DM ... lesser extent, DM ... • Anti-MDA5 DM
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
, with: 1) heliotrope ... rash, 2) shawl ... and 3) Gottron's papules ... HeliotropeRash #Gottrons #Papules ... #Clinical #Photo
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... (DM) and Polymyositis ... Pathogenesis and clinical ... /- swelling -> Heliotrope ... Rash - Dysphagia
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
rash, shawl sign ... and Gottron's papules ... rash, 2) shawl ... #dermatology #clinical ... #photo
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
DM with generalized ... to have typical DM ... • Periorbital heliotrope ... (blue-purple) rash ... Clinical and
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Symptoms: • Gottron rash ... (Gottron papules ... Shawl sign • Heliotrope ... Antisynthetase syndrome ... elevated < PM and DM