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allergy diagnosis hypersensitivity reactions table comparison ddxof definitions pathophysiology peds sbi seriousbacterialillness
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
, seasonal hay fever ... to complement activation ... Antigen-antibody complexes ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
lgE causes mast-cell ... Anaphylaxis, Hay fever ... to complement activation ... Antigen-antibody complex ... #classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... antigen-surface complex ... causes development ... because T-Cell activation ... #Types #Classification
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
pyelonephritis Most common cause ... Consider BCx, CSF evaluation ... (particularly complex ... Diagnosis #Peds #EM ... #Classification
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