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diagnosis differential shock allergy reactions criticalcare hypersensitivity pathophysiology rheumatology table treatment hematology hemophagocytic hlh lymphohistiocytosis neurology overview allergic angioedema antiarrhythmics
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... Allergen-specific lgE causes ... antigens, leading ... to complement activation ... allergy #table #classification
Pathogenesis of Rheumatic Fever Pathogenesis of rheumatic fever. 1. GAS pharyngitis leads to antigenic presentation of pathogenic
peptides to T-cells ... by endothelial activation ... facilitates T-cell ... Exposure of Type-IV ... antibodies which can cause
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... surfaces causes ... exposure to allergen causes ... activation takes ... #Classification
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... → Excessive activation ... , Hb), Hepatic dysfunction ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... in > 90% of cases ... #Types #Diagnosis ... #Treatment #management
Shock Types - Classification State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... water #Shock #Classification ... #management #criticalcare
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... pulmonary Langerhans cell ... #Differential #Causes
Shock Classification Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... #Types #diagnosis ... #management #cold
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
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