15 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... • Liver (80%) ... Intestine - Other causes ... #hepatology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
hyperplasia of bone ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... candidate) - Bone ... #Diagnosis #Causes ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... • Pernicious anemia ... mineralization Symptoms ... Phosphatase: • Other causes
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential # ... Diagnosis
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
be used by the bone ... is made in the liver ... Hematologic Malignancy ... Sideroblastic anemia ... #Diagnosis #Causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Drug induced - Bone ... - Hemolytic anemia ... deficiency • Liver ... #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... PBC Signs and Symptoms ... PBC Labs: • Alkaline ... bile ducts Differential ... #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... syndrome, Congestion/CHF ... hemolysis) • ALP: Bone
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... AnemiaBone ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology