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differential hematology algorithm alkaline abnormal biliary cholangitis cirrhosis classification disorders elevation enzymes hepatitis hodgkins hyophosphatasia injury leukemia lfts low lymphoma
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... • Liver (80%) ... Intestine - Other causes ... symptoms - Pain ... #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... Most cases diagnosed ... mineralization Symptoms ... : • Other causes ... #hepatology #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular Causes ... syndrome, Congestion/CHF ... : Bone, first trimester ... #algorithm #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... pylori test (GI symptoms ... candidate) - Bone ... #Causes #Workup ... #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... Areas of diagnostic ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... PBC Signs and Symptoms ... : • Alkaline phosphatase ... obstruction • ALP ... #workup #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... Symptoms: • Malaise ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... anymore • Routine bone ... #oncology #management
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