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hematology management differential gammopathy leukemia monoclonal significance cell chronic essential et hemeonc hemophagocytic hlh hodgkins infections infectiousdiseases lymphocytic lymphohistiocytosis lymphoma
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... -> AML: Blast crises ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... pylori test (GI symptoms ... candidate) - Bone ... #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... lymphoproliferative disorders ... Warm AIHA • Bone ... #workup #oncology ... #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... and classification ... to 50% of PTLD cases ... Lymphoproliferative #Disorders ... #oncology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... age 70 years Symptoms ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... anymore • Routine bone ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Hematologic disorder ... constitutional symptoms ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... massiliense in CF ... gastrointestinal symptoms ... ) - Bone Marrow ... • Clinical (Symptoms
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... Biopsy: Solitary disorder ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... When present, symptoms ... • "Vasomotor" symptoms ... 450,000/microL • Bone ... hemoproliferative disorder
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