6 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... Hodgkin lymphoma and leukemia
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - PNH - APLS ... vasculitis - GPA ... Differential #Diagnosis #hematology ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Hepatomegaly • Skin ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... differential #diagnosis #hematology