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diagnosis differential rheumatology hematology causes vasculitis activation cryoglobulins elevation high hyperkalemia lactate lactic macrophage management mas monoclonal nonpalpable oncology palpable
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... diseases: - 10% SLE ... lupus erythematosus ... (SLE), rheumatoid ... diagnosis #types #classification
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... is found in the bone ... Diagnosis #Management #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: • Vascular occlusion ... Drug induced - Bone ... Splenomegaly - CTD (SLE ... vasculitis/HSP • Cryoglobulinemia ... Associated - SLE
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
neuropathy) • Systemic ... Immunotactoid GN & Cryoglobulinemic ... WM: Vasculitis (Cryoglobulinemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ANCA +MPO) • Cryoglobulinemic ... lupus erythematosus ... reactions, and vaso-occlusive ... vasculitis, and SLE ... #rheumatology #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
again we might see ... disease states one ... One of these is ... of Circulatory System ... #typea #typeb #classification
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Acidosis B. ... lupus erythematosus ... (SLE), sickle cell ... Tubulointerstitial diseases: SLE ... High #Potassium #Classification
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