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diagnosis differential hematology causes algorithm classification criticalcare hemolytic lactate oncology rheumatology systemic testing acid agitation alkalosis arthritis base cell chronic
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis 1) Start with the Anion Gap (AG). 2)
Approach to Acid Base Disorders ... delta/delta) to see ... chronic) of the disorder ... : Lactic Acidosis ... #Evaluation #workup
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... DKA, Alcoholic lactic ... @nickmmark #Lactic
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... - Drugs (Beta lactam ... #anemia
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... Iron deficiency anemia ... discoloration) • Chronic renal ... Systemic #Secondary #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) • Endocrine disorders ... dysfunction, and mood disorder ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactate Elevation, Lactic ... Acidosis - Differential ... again we might see ... Acidosis: Hypoxic ... 30mmHg) - Severe anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... genotypes): SS, SC, SE ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
syndrome (PRIS) - acidosis ... , bradycardia. renal ... drug, it causes amnesia ... can result in lactic ... acidosis.
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... metabolic or endocrine disorders ... Arthritis #laboratory #workup
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