4 results
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... , retinal, DVT, ... Differential #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
No evidence of anemia ... hyperCalcemia, Renal ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
dL the ULN R - Renal ... 40 ml/min A - Anemia ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Gammopathy Include: • MGUS ... cancers, HCC, renal ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia