10 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • XR, MRI to ... #Joint #Pain #SickleCell ... #diagnosis #causes ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Bone and joint ... anterior chest wall, parts ... - MRI: inflammation ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Pain Rash ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Tendon • Ligament ... #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Freiberg Infraction - MSK Radiology
Imaging Findings:
 • Sclerosis of the 2nd MT head with flattening of
factors include: Short ... • Pain worsens ... Differential diagnosis ... plate, subchondral bone ... foot #clinical #mri
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... burning sensation or pain ... reticularis Differential ... #rash #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints ... #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Pinpoint-sized red spots ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
vesicular eruption • Joints ... , mucositis • Rash ... oligoclonal bands • MRI ... Palpable purpura, joint ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hemolytic anemia • Pain ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... classification #hematology