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diagnosis management rheumatology anemia aplastic behcet chronic cll cryofibrinogenemia differential disease leukemia lymphocytic monoclonal paraproteinemias signs workup
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt+, ↑thrombosis ... Hyperviscosity (Thrombosis ... beds-renal, retinal, DVT ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... necrosis) - Thrombosis ... Biopsy: Typical pathologic ... Antiphospholipid syndrome ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... Venous disease (SVC ... , dural sinus thrombosis ... (Clinical Dx). ... #rheumatology #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
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