8 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... Edoxaban #Loading #DVT ... #Pharmacology #
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... DVT = deep vein ... thrombosis; PE = ... Cancer #Algorithm #Anticoagulation ... Management #Hematology #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... rivaroxaban, and apixaban ... Rivaroxaban and apixaban ... #Chemotherapy #Oncology ... Interactions #Table #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... interruption per treatment ... may not require anticoagulation ... inhibitor) • Apixaban ... #pharmacology #
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
catheter-related thrombosis ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... Management #Hematology #Oncology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT) - Diagnosis ... 5-10d, venous (DVT ... thrombocytopenia Diagnosis ... , Bivalirudin, DOAC ... #Management #Treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
or small-vessel thrombosis ... to be present Treatment ... Guidelines): • Anticoagulation ... target to 3-4 • DOACs ... #management #anticoagulation
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
erythromelalgia • Thrombosis ... MI, stroke, DVT/ ... Splenomegaly Diagnosis ... A conclusive diagnosis ... Hydroxyurea + anticoagulation