49 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... it is entirely T-Cell ... causes development ... T-Cell response ... exposure, because T-Cell
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... with cytotoxic T ... IV - T cells - ... and cytotoxic T ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... T-cells recruit ... #allergy #table ... #classification
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Target: Modified cell ... Immunological Mediator: Th Cells ... #Types #Classification
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
reactions Type ... (Anaphylaxis) Type ... IV T-Cell-Mediated ... #Classification ... #Allergy #Diagnosis
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
surfaces causes ... it is entirely T-Cell ... T-Cell response ... exposure, because T-Cell ... #Types #Classification
Allergic Contact Dermatitis 
- Erythematous, indurated, scaly plaques 
- T-cell mediated, delayed-type hypersensitivity response to exogenous
Allergic Contact ... scaly plaques - T-cell ... mediated, delayed-type ... Contact #Dermatitis #Allergic ... #Allergy #Dermatology
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... in > 90% of cases ... is key • Mast cell-mediated ... #Types #Diagnosis
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... infection - Allergic ... : - B or T cell ... CD3-CD4+ T cells ... ) - Allergic bronchopulmonary
Trunk / Sacral Skin Ulcers - Differential Diagnosis Algorithm
Neoplastic
 • Squamous cell carcinoma
 • Basal cell
Differential Diagnosis Algorithm ... carcinoma • Basal cell ... fungoides (cutaneous T-cell ... Differential #Diagnosis #Algorithm ... #causes