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differential management neurology bee clinical crypto cryptococcal meningitis myelitis neuritis noninflammatory ophthalmology optic radiology sjogrens syndrome syndromes t2 transverse vasculitis
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Unilateral • Signs ... R-G or B-Y • MRI ... anterior lesions (a), Brain ... other auto-immune diseases ... #rheumatology #
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... ruled out • Brain ... brain and/or optic ... , Hep A/B/CMV, TB ... Transverse Myelitis Treatment
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
affecting the Brain ... , Eye, and Ear ... and treatment can ... neuropathy (LHON) plus MRI ... consistent with MS
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... purpura: Strong sign ... oligoclonal bands • MRI ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
: • 10%-15% Pulmonary ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... Symptomatic: artificial tears ... Sjogrens #Syndrome #Rheumatology
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
DDX Tb meningitis ... of prior silent pulmonary ... organism (soap bubble sign ... Standard treatment ... #Brain #clinical
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