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management differential rheumatology clinical multiple sclerosis syndrome bee behcet brain criteria crypto cryptococcal half mcdonald meningitis myelitis neuritis noninflammatory one
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis (MS ... neurodegenerative disease ... nearly 3:1 • MS ... resonance imaging [MRI ... #treatment #MS
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... swollen, while in MS ... Predictive of MS ... Multiple sclerosis (MS ... , Hep A/B/CMV, TB
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Unilateral • Signs ... R-G or B-Y • MRI ... - Typical MS-like ... other auto-immune diseases ... #rheumatology #ophthalmology
McDonald Criteria for Diagnosis of Multiple Sclerosis • 2 or more attacks, 2 or more lesions
McDonald Criteria for Diagnosis ... from onset - One year ... of disease progression ... Multiple #Sclerosis #MS ... #neurology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Brain, Eye, and Ear ... and treatment can ... neuropathy (LHON) plus MRI ... consistent with MS ... BEE #Syndromes #neurology
One and a Half Syndrome on Physical Exam This 28 year old patient presented to clinic with
MRI was ordered ... the hospital, diagnosed ... with MS, and started ... Half #Syndrome #PhysicalExam ... #neurology
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 Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... Giant retinal tears ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology ... #management #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... affects the skin, neurologic ... cognitive impairment, neurologic ... oligoclonal bands • MRI
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
DDX Tb meningitis ... of prior silent pulmonary ... organism (soap bubble sign ... Standard treatment ... University Infectious Diseases
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