48 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... infiltration) Differential ... Diagnosis: Viral ... Maternal Support - Critical ... #Pregnancy #hepatology
Problem Representation

An evolving summary of a patient’s clinical presentation that strives to identify 
(1) Clinical syndrome
of a patient’s clinical ... syndrome (signs ... /symptoms), (2) ... • One-liner at start ... • Educating a team
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology ... #Differential # ... Diagnosis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... renal failure Clinical ... heart (2-5%), liver ... #Management #Signs
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... #Diagnosis #causes ... #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... the spleen or liver ... Diagnosis of B-Symptoms ... #differential # ... hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Elevation of ALP • Near ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Brain, Eye, and Ear ... conjunction with symptoms ... MRI lesions and clinical ... noninflammatory #differential ... #diagnosis