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management differential ankle autoinflammatory behcet classification clinical cryofibrinogenemia disease e1 hematology impingement mri myelitis neurology os ostrigonum polychondritis posterior relapsing
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Features: alveolitis, ear ... recurrent fevers, vasculitis ... (MDS) Most met criteria ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • Cogan Syndrome ... well as inner ear ... Presentation - Systemic Symptoms ... #rheumatology #
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology Imaging Findings: • Os trigonum which has marrow
(Os Trigonum) Syndrome ... - MSK Radiology ... syndesmotic ligament tear ... flexion but no symptoms ... #diagnosis #msk
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... meningitis), MCC CNS symptoms ... Giant retinal tears ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... Presentation: Systemic Symptoms ... • Progressive symptoms ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... Cryofibrinogenemia Diagnosis ... Antiphospholipid syndrome ... #rheumatology #
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... Criteria: • Sensory ... Bilateral signs and/or symptoms ... Transverse Myelitis Diagnosis ... - Sjogren - Vasculitis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... phenomenon (16%) MSK ... Symptomatic: artificial tears ... #Rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... and fatigue Criteria ... Polychondritis #rheumatology ... #diagnosis #management
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