22 results
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
- Differential ... Diagnosis Workup ... apoplexy • Isolated ACTH-deficiency ... #Diagnosis #Workup ... #Algorithm #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis ... Algorithm Clinical ... ) stimulation test ... #Diagnosis #Algorithm ... #endocrinology
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm
Exogenous (ACTH-independent)
Endogenous
 • ACTH-dependent:
    - ACTH-secreting
) - Simplified Differential ... Diagnosis Algorithm ... : - Adrenal ... #Diagnosis #Algorithm ... #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal ... Insufficiency - Algorithm ... Step 3) Differentiate ... #Diagnosis #ACTH ... #Stimulation #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
stimulation test ... atrophied from a long-term ... Evaluation #laboratory #diagnosis ... #testing #endocrinology ... #workup
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Diagnosis Algorithm ... Standard Stim test ... #Algorithm #ACTH ... #Stimulation #Test ... #Endocrinology
Benign Adrenal Mass - Differential Diagnosis Algorithm
Hyperplasia - Often Bilateral
 • Congenital Adrenal Hyperplasia
 • ACTH
- Differential ... Diagnosis Algorithm ... Dexamethasone Suppression Test ... #Diagnosis #Algorithm ... #Endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Insufficiency - Differential ... Diagnosis Algorithm ... ACTH-Dependent ... #Diagnosis #Algorithm ... #Causes #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... Diagnosis Algorithm ... Test 1: Baseline ... 2: ACTH Stimulation ... #Algorithm #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Diagnosis Algorithm ... skin (due to high ACTH ... cosyntropin stimulation test ... interact with stim test ... Stimulation #StimTest #Endocrinology