17 results
Shotgun Laboratory Testing for Severe Acute Livery Injury

https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known

#TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
for Severe Acute Livery ... Injury https ... ammonia-levels-and-hepatic-encephalopathy-patients-known ... LiverInjury #Diagnosis #Workup ... #Hepatology #EBM
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... injury) • Ischemic ... ) • Non-hepatic ... #Function #Tests ... Differential #Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... #Injury #Differential ... Acute #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Alcohol-Associated Hepatitis ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... test abnormalities ... • Infections: Hepatitis ... #Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
disease, Hepatic ... presentation: Hepatic ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Injury: • Hepatic ... extrahepatic source - Tests ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
inhibitor • Liver ... elevated in: • Heparin ... • Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
) or metabolic liver ... Possible drug-induced liver ... Presence of atypical laboratory ... tests (e.g., AST ... #Diagnosis #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... replaced by non-hepatic ... Chronic viral hepatitis ... #differential #Hepatology