29 results
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Positive serologic testing ... first year of infection ... • Gummatous • Nodular ... • Time of infection ... symptoms #signs #diagnosis
Differential diagnosis of Skin + Eye infections
 • Bacterial: Staph spp, Strep spp, Pseudomonas spp, Bartonella,
Differential diagnosis ... of Skin + Eye infections ... ] #skin #eye #ocular ... #dermatology #InfectiousDiseases ... #Diagnosis #viral
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
INDICATIONS FOR TESTING ... drug reaction, infection ... Strongyloides infection ... #Differential #diagnosis ... #hematology #eosinophilia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... Positive Coombs testing ... setting - Mycoplasma ... hemolytic #anemia #hematology ... #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... testing for HLH-associated ... Treatment: • Infection ... Supportive measures and treating ... management #treatment #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... - Trauma - Infection ... • Abdominal ultrasound ... Algorithm #Causes #dermatology ... #physicalexam
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
to heat (fires, heating ... pads, heating blankets ... acquired dermal macular ... #differential #diagnosis ... #dermatology #compared
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... inclusions - If infection ... #Differential #Diagnosis ... Algorithm #workup #hematology ... #testing
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... related vasculitis, infections ... IgM deposits • Nodular ... Vasculitis #skin #dermatology ... #differential #diagnosis
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... counts may delay diagnosis ... especially in the setting ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology