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diagnosis management cppd gout approach calcium degenerative differential druginduced fungal infections infectiousdiseases inflammatory joint jointdisease jointpain lupus mycoses pain pseudogout
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... Crystal Deposition ... ochronosis and crystal deposition ... #Joint #Pain #MSK ... #rheumatology #
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... Monosodium urate deposition ... #CPPD #Gout #Comparison ... #rheumatology #
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... in Rheumatoid arthritis ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... JointPain #Diagnosis #pathophysiology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition ... Pathophysiology ... Acute Pseudogout: Treatment ... Pyrophosphate #Deposition ... #Disease #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... life-threatening • Treatment ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Monosodium urate deposition ... frequent attacks • Arthritis ... Dual-energy CT → MSU ... • Acute gout treatment ... #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... extrapulmonary disease ... or meningitic disease ... Aspergillosis Pathophysiology ... Meningitis, septic arthritis
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