3 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... Positive Coombs testing ... • Compensated hemolysis ... IgM) • Blood smear ... post infectious setting
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Agglutination - Cold ... (oroya fever), babesia ... #Differential #Diagnosis ... workup #hematology #testing
Babesiosis - Diagnosis and Management Summary 
Disease: Release of merozoites from erythrocytes and associated loss of
integrity causing hemolysis ... • Thin blood smear ... (useful in the setting ... identification • IgM antibody ... #Babesiosis #Babesia