18 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... cells can indicate disease ... Leukemia #diagnosis #workup ... #oncology #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... cells: Sickle cell ... disease Bite cells ... #Analysis #hematology ... interpretation #clinical
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... Aggressive disease ... primary plasma cell ... rouleaux #formation #Clinical ... #Smear #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... peripheral blood smear ... PT, aPTT(liver disease ... not required in all ... #hematology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Fractional excretion of Cl ... > 0.5% Clinical ... autosomal dominant kidney ... disease Renal Imaging ... #nephrology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoid malignancy (CLL ... Viral Infection Clinical ... IgM) • Blood smear ... malignancies -> CLL ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... • Peripheral smear ... immunophenotype Clinical ... chemotherapy for low-risk disease ... uw_IMresidency #CLL
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... myalgia, serositis, Kidney ... Evolution: Chronic disease ... comparison #table #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... lesions, meninges, kidneys ... management #phenotypes #workup ... #treatment #rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... oxygen sensing (at kidneys ... you’ll do a good workup ... can drive this disease ... As with many disease