15 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... Refractory ITP, ... #Workup #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... , vomiting, abdominal ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... DIC • Severe Liver ... Treat primary cause
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
ileus), intra-abdominal ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus #
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hyperviscosity, TTP ... Syndrome, Ischemic Liver ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Transfusing blood ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
the setting of liver ... lung disease Caused ... passage • Arterial blood ... contrast-enhanced TTE ... management #treatment #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... deficiency • blood ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Purpura (PTP ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... more likely to cause
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Purpura (PTP ... Causes purpura & ... TRALI): Leading cause ... eruptions, diarrhea, liver ... diagnosis #management #hematology