13 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... Refractory ITP, ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... , vomiting, abdominal ... ) Differential Diagnosis ... #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... DIC • Severe Liver ... #Coagulation #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Hyperviscosity, TTP ... Syndrome, Ischemic Liver ... Venous #Arterial #pathophysiology ... #diagnosis #vascular
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
the setting of liver ... lung disease Caused ... passage • Arterial blood ... contrast-enhanced TTE ... management #treatment #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... deficiency • blood ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Purpura (PTP ... Causes purpura & ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Transfusion Purpura (PTP ... Causes purpura & ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... , weight loss, abdominal ... Cytopenias • AIHA, ITP ... #Leukemia #Hematology ... #Oncology #Diagnosis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of hemolysis or liver ... symptoms, such as abdominal ... and stress may cause ... bilirubin in the blood ... #diagnosis #gastroenterology