23 results
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... reduction in ATP ... pathway away from ATP ... Phosphate is a cause ... respiratory #hypoxia #pathophysiology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... autoantibodies - TPO, TTG ... SPS #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... Schistocytes - MAHA: TTP ... Treat primary cause ... #treatment #management
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... nonimmune hemolysis MSK ... • Weakness • Muscle ... , or any other cause ... periodontitis • ITP
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Fairly symmetric muscle ... • Respiratory Muscle ... Syndrome #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... , muscle atrophy ... Escorial criteria uses ... neurology #diagnosis #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... fluid into injured muscles ... Differential #Diagnosis #Management ... #Summary #causes
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... symptoms are not caused ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
in diminished muscle ... Respiratory muscles ... : “myasthenic crises ... immunologic assay - MuSK ... Gravis #diagnosis #management
Clostridial myonecrosis of deltoid muscle on POCUS

Right shoulder pain case.  Diabetic male with nontraumatic shoulder
myonecrosis of deltoid muscle ... on POCUS Right ... shoulder pain case ... #POCUS #clinical ... #MSK #ultrasound