13 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
in diminished muscle ... : “myasthenic crises ... Generalized fatigue - ALS ... Diagnosis - ... #management #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
: • Based on clinical ... but 5% have anti—muscle-specific ... likely to cause ... - Improves clinical ... #management #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... Motor Nerves: ALS ... Eaton Syndrome, Myasthenia ... aminoglycosides) • Muscles ... #differential #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... lateral sclerosis Pathophysiology ... cellular function Clinical ... - Causes progressive ... #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... Clinical Manifestations ... #Management #treatment
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
Disease (HADD) - MSK ... seen within the deltoid ... muscle fibers and ... Case description ... #msk
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... #management #treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
and Management ... poor nutrition Clinical ... nonimmune hemolysis MSK ... • Weakness • Muscle ... , or any other cause
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... survival is 93-95% Pathophysiology ... renal failure Clinical ... mediators such as ... anterior/posterior MSK
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... fairly symmetric muscle ... the underlying pathophysiology ... #management #neurology