12 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
in diminished muscle ... Respiratory muscles ... myasthenia Diagnosis ... immunologic assay - MuSK ... #diagnosis #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... but 5% have anti—muscle-specific ... More likely to cause ... #Myasthenia #Gravis ... #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... Person Syndrome Treatment ... #Management #treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Guillain-Barre Diagnosis ... Barre #Syndrome #diagnosis ... #management #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... and Management ... Dermatomyositis) AKI - Pathophysiology ... fluid into injured muscles ... #causes #treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
and Management ... nonimmune hemolysis MSK ... • Weakness • Muscle ... , or any other cause ... vasculitis Treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... Escorial criteria uses ... column Treatment ... #management
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Sanguinis, Mitis, Oralis ... Septic Emboli Cause ... Treat underlying cause ... gallolyticus, clostridium ... #management #cardiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... fairly symmetric muscle ... the underlying pathophysiology ... and cauda equina TREATMENT ... #management #neurology