10 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
in diminished muscle ... Respiratory muscles ... : “myasthenic crises ... immunologic assay - MuSK ... #diagnosis #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... but 5% have anti—muscle-specific ... More likely to cause ... #Myasthenia #Gravis ... #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... Person Syndrome Pathophysiology ... Person Syndrome Treatment ... #treatment #neurology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... + Bleeding Treatment ... Treat primary cause ... #treatment #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Treatment: • Plasmapheresis ... Syndrome #diagnosis #management ... #treatment #neurology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... fluid into injured muscles ... #Summary #causes ... #treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... nonimmune hemolysis MSK ... • Weakness • Muscle ... , or any other cause ... vasculitis Treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... Escorial criteria uses ... diagnosis column Treatment ... neurology #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... fairly symmetric muscle ... the underlying pathophysiology ... and cauda equina TREATMENT ... Syndrome #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... • Infectious causes ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management