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Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
genital aphthous ulcers ... to exclude are infections ... purpura: strong sign ... Cryoglobulins • HIV ... #rheumatology #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Purpura - Skin ulcers ... : • Clinical triad ... : HCV infection, ... HBV infection, ... HIV infection
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... to exclude are infections ... purpura: Strong sign ... • Cogan syndrome
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
: • Syndrome of ... grp IV): Pulmonary ... (buruli ulcer) ... Disease: Clinical ... #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... • CT: Halo sign ... • Oral mucosal ulcers ... #HIV #AIDS #pulmonary ... #infectiousdiseases
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... sensitivity • Painful ulcers ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Bilateral signs ... simplex virus, HIV ... - Sjogren - Vasculitis