14 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Trauma: Shock liver ... syndrome, Portal vein ... • Autoimmune hepatitis ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
- Acute Viral Hepatitis ... , Toxic Hepatitis ... cirrhosis, Portal Vein ... #Injury #hepatology ... #LFTs #transaminitis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... serologic evidence of hepatitis ... Chronic Hepatitis ... .2018.3795 #Chronic #HepatitisB ... #HBV #Algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... Differential #Diagnosis #hepatology ... #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... A/B/C/D/E, EBV, ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... mg/dL) or acute liver ... failure #HepatitisB ... #HepBV #HBV #Treatment ... Indications #management #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... NAFLD, Autoimmune hepatitis ... Pregnancy, Alcoholic Hepatitis ... Sepsis, Viral Hepatitis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Chronic viral hepatitis ... #differential #Hepatology ... #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
: • Hepatic vein ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... #injury #hepatitis ... #hepatology