17 results
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... especially penis) Wickham's ... soles • Discoid Lupus ... sun-exposed area #Papulosquamous
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... lupus erythematosus ... lupus erythematosus ... : Evidence of macrophage ... Syndrome #Diagnosis #Management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... , oral ulcers, Lupus ... #Systemic #Erythematosus ... #Diagnosis #Management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... • MCTD (SLE/systemic ... @AnnKumfer #Systemic ... #Lupus #Erythematosus ... #rheumatology #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Lupus Erythematosus ... Diagnosis of Lupus ... RheumOnePagers) #Systemic ... cerebritis #diagnosis #management
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... killer cells, macrophages ... arthritis, and systemic ... lupus erythematosus ... which activate macrophages
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Acute cutaneous lupus ... polyclinic or patchy papulosquamous ... Neuropsychiatric systemic ... papillomavirus #SLE #Systemic
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... months to years) Systemic ... Usual therapeutic management ... rheumatology #diagnosis #management
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
glomerulonephritis, Systemic ... lupus erythematosus ... T-cells recruit macrophages
Renal involvement in Systemic Lupus Erythematosus (SLE)

Dr. Laurent ARNAUD @Lupusreference

#Renal #lupus #nephritis #SLE #Systemic #Erythematosus #SLE
involvement in Systemic ... Lupus Erythematosus ... Lupusreference #Renal #lupus ... nephritis #SLE #Systemic ... Erythematosus #SLE #management