Lingual Papillomas - He had macrocephaly (head circumference in the >97th percentile), as well as multiple trichilemmomas (benign flesh-colored papules) on the face and chest and acral keratosis (wartlike papules) on the hands and feet. He was also noted to have lingual papillomas, which he recalled had been present for many years. The patient had a history of hyperplastic and adenomatous gastrointestinal polyps and a multinodular goiter. #Clinical #Genetics #Honc #LingualPapilloma #Cowden #CowdenSyndrome #Hamartoma #PTEN #NEJM
