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Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis → diuresis → hypovolaemia 4) Hypovolaemia → ADH → water reabsorption 5) ↓ Na+ → Subclinical volume expansion → Increased urine volume, hypovolaemia → treat with fluid therapy → rare - Dr. Sinead Stoneman @Stones__ #Cerebral #SaltWasting #SIADH #Pathophysiology #diagnosis #nephrology #hyponatremia #comparison