High Anion Gap Metabolic Acidosis (HAGMA) - Mnemonics Why should we switch from MUDPILES to GOLDMARK? • Metabolic acidosis due to excessive paraldehyde or phenformin use has become very rare. • Iron and isoniazid are just two of many drugs and toxins that can cause hypotension and lactic acidosis. Isoniazid can also generate a component of ketoacidosis. • Three new organic acids and acid precursors have been recognized as causes of AGMA: 1) D-lactate, 2) 5-oxoproline, 3) propylene glycol #AnionGap #Metabolic #Acidosis #HAGMA #Mnemonic #GOLDMARK
