Post-Transplant Diarrhea - Diagnosis and Management Algorithm Post-transplant diarrhea (≥ 3 loose or liquid stools per day) • Malabsorption workup in case of chronic diarrhea • Stop non immunosuppressive drugs associated with diarrhea • First-line microbiological stool Investigations (#) ± Plasma CMV PCR Adaptation of IS drug regimen • MMF dose reduction or switch to EC-MPS or switch to Aza if MPA dose < 50% doses recommended (Norovirus++) • Tacrolimus dose reduction (5-8 ng/mL) or switch to cyclosporine • mTORi withdrawal, switch to CNI • CNI withdrawal, switch to mTORi #Transplant #Diarrhea #Diagnosis #Management #Algorithm #nephrology #renal #kidney
