Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute Prosthetic Valve Dysfunction, Post Acute Balloon Valvuoplasty • Aorta: Acute Aortic Dissection, Traumatic Injury to Root Chronic - Leaflet: • Infection: Infective Endocarditis, Rheumatic Fever, Whipple Disease • Inflammatory: Lupus, Rheumatoid Arthritis, Ankylosing Spondylitis, Takayasu Arteritis, Crohn Disease • Structural: Calcific AoV, Bicuspid AoV, Unicuspid or Quadricuspid AoV, Congenital Aortic Regurgitation, Myxomatous Degeneration, Prosthetic Valve Dysfunction Chronic - Aorta: • Infxn + Inflammatory: Infectious Aortitis (i.e., Syphilis, Salmonella), Giant Cell Arteritis, Takayasu Arteritis, Behcet Syndrome, Relapsing Polychondritis, Reactive Arthritis, Psoriatic Arthritis, IgG4 Disease, Cogan's Disease • Genetic Aortopathy: Osteogenesis Imperfecta, Ehlers-Danlos Syndrome, Marfan's Loeys-Dietz, Sporadic Thoracic Aortic Aneurysms and Dissection • Degenerative: Systemic Arterial Hypertension, Age-Related Aortic Dilation - Cardionerds - Karan Desai MD, MPH @karanpdesai #Aortic #Regurgitation #Differential #Diagnosis #Causes #cardiology
