Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick — Ixodes scapularis • Infects granulocytes, within morulae Signs and symptoms: • 5-14 days after bite • Fever, headache, malaise, myalgias, shaking chills • Rash is rare (< 10% cases), cough (30% cases) Laboratory findings • Leukopenia (though increased immature forms) • Anemia and thrombocytopenia • Elevated transaminases - BWH Medicine Chiefs @BrighamChiefs #Anaplasma #Infection #diagnosis #microbiology #geography
