Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin necrosis), Trauma, Drugs • Vasculopathy - Deposition: Paraproteins, Calciphylaxis • Vasculopathy - Emboli: Septic, Cholesterol • Vasculopathy - HyperC: APLS, PV/ET • Leukocytoclastic Vasculitis (LCV), Immune complex mediated (cryoglobulins, IgA), ANCA associated small vessel BWH Medicine Chiefs @BrighamChiefs #Purpura #nonpalpable #palpable #Causes #Differential #Diagnosis #vasculitis
