Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly in younger patients and in those with a history of prior venous thromboembolism (VTE).
(Inherited thrombophilias are not a major risk actor for arterial thrombosis)
Venous thromboembolism:
• Provoked (e.g. surgery, trauma, active malignancy, immobilization)
- Age-appropriate cancer screening (in absence of an established malignancy)
- No other workup typically indicated
• Unprovoked
- Everyone → Age-appropriate cancer screening, CBC, aPTT, +/- CXR
- Recurrent VTE → Inherited and APS
- Age < 45-50 years of age → Inherited and APS
- Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi
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