Indications for tPA in Stroke: • Clinical diagnosis of ischemic stroke • Measurable neurologic deficit • Onset of symptoms < 4.5 hours prior to intravenous tPA administration (unless age >80 or other less common features are present, in which case onset must be < 3 hours) Absolute Contraindications to tPA (incomplete list): • Ischemic stroke, head trauma, or neurosurgery (intracranial or intraspinal) within previous 3 months • Previous intracranial hemorrhage • Active internal bleeding • Intracranial neoplasm, AVM, or aneurysm • SBP > 185mmHg or DBP > 110mmHg • Platelet count < 100,000/mm3 • Therapeutic anticoagulation • Arterial puncture at noncompressible site within the past 7 days - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #Indications #tPA #Stroke #cva #management #neurology
